Role of CRD-BP in the growth of human Basal Cell Carcinoma Cells

  title={Role of CRD-BP in the growth of human Basal Cell Carcinoma Cells},
  author={Felicite K Noubissi and TaeWon Kim and Tisha N. Kawahara and William D. Aughenbaugh and Eric. Berg and B. Jack Longley and Mohammad Athar and Vladimir S. Spiegelman},
  booktitle={The Journal of investigative dermatology},
Although the number of new cases of basal cell carcinoma (BCC) has increased rapidly in the last few decades, the molecular basis of its pathogenesis is not completely understood. Activation of the Hedgehog (Hh) signaling pathway has been shown to be a key factor driving the development of BCC. The Wnt/β-catenin signaling pathway was also shown to be activated in BCCs and to perhaps modulate the activity of the Hh pathway. We have previously identified a mechanism by which Wnt signaling… CONTINUE READING
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