Role of CMV in immune senescence.

  title={Role of CMV in immune senescence.},
  author={Graham P Pawelec and Evelyna Derhovanessian},
  journal={Virus research},
  volume={157 2},
"Immune senescence" is a descriptive term for the deleterious age-associated changes to immunity observed in all mammals studied so far. While all components of innate and adaptive immunity are changed with age, the clinical impact of these changes is not clear, and mechanisms of and markers for immunosenescence are controversial. In humans, several cross-sectional studies have demonstrated that the major accepted age-associated changes to parameters used to assess adaptive immune status are… CONTINUE READING

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