Role of CCL-2, CCR-2 and CCR-4 in cerulein-induced acute pancreatitis and pancreatitis-associated lung injury.

@article{Frossard2011RoleOC,
  title={Role of CCL-2, CCR-2 and CCR-4 in cerulein-induced acute pancreatitis and pancreatitis-associated lung injury.},
  author={Jean-Louis Frossard and S{\'e}bastien Lenglet and Fabrizio Montecucco and Sabine Steffens and Katia Galan and Graziano Pelli and Laurent Spahr and François Mach and Antoine Hadengue},
  journal={Journal of clinical pathology},
  year={2011},
  volume={64 5},
  pages={
          387-93
        }
}
BACKGROUND AND AIMS Acute pancreatitis is an inflammatory process of variable severity. Leucocytes are thought to play a key role in the development of pancreatitis and pancreatitis-associated lung injury. The interactions between inflammatory cells and their mediators are crucial for determining tissue damage. Monocyte chemoattractant protein-1 (or CCL-2), CCR-2 and CCR-4 are chemokines and chemokine receptors involved in leucocyte trafficking. The aim of the study was to evaluate the role of… CONTINUE READING
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