Role of CB2 receptors in neuroprotective effects of cannabinoids

@article{FernndezRuiz2008RoleOC,
  title={Role of CB2 receptors in neuroprotective effects of cannabinoids},
  author={Javier Fern{\'a}ndez-Ruiz and Mar{\'i}a Ruth Pazos and Mois{\'e}s Garc{\'i}a-Arencibia and Onintza Sagredo and Jos{\'e} Antonio Ramos},
  journal={Molecular and Cellular Endocrinology},
  year={2008},
  volume={286},
  pages={S91-S96}
}
CB2 receptors, the so-called peripheral cannabinoid receptor type, were first described in the immune system, but they have been recently identified in the brain in healthy conditions and, in particular, after several types of cytotoxic stimuli. Specifically, CB2 receptors were identified in microglial cells, astrocytes and, to a lesser extent, in certain subpopulations of neurons. Given the lack of psychoactivity demonstrated by selective CB2 receptor agonists, this receptor becomes an… 
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