Role of BDNF Val66Met functional polymorphism in Alzheimer's disease-related depression.

Abstract

BACKGROUND The gene encoding brain-derived neurotrophic factor (BDNF) has been suggested as a candidate for major depression, and for depression susceptibility in different neurological and psychiatric diseases. No study has investigated the role of BDNF genetic variation and depressive symptoms in Alzheimer's disease (AD). OBJECTIVE The aim of this study… (More)
DOI: 10.1016/j.neurobiolaging.2007.11.023

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