Role of B cells in presentation of autoantigens to CD4+ T cells in patients with autoimmune thyroiditis

Abstract

The antigen-presenting activity of B cells and expression of molecules involved in antigen presentation by B cells have been studied in patients with autoimmune thyroiditis (AIT). The disease is characterized by enhanced expression of the costimulatory molecule CD80 in naive B cells (CD19+CD27− cells) both ex vivo and under the conditions of polyclonal cell… (More)
DOI: 10.1134/S0012496615050099

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