Role of Arg-72 of pharaonis Phoborhodopsin (sensory rhodopsin II) on its photochemistry.

@article{Ikeura2004RoleOA,
  title={Role of Arg-72 of pharaonis Phoborhodopsin (sensory rhodopsin II) on its photochemistry.},
  author={Yukako Ikeura and Kazumi Shimono and Masayuki Iwamoto and Yuki Sudo and Naoki Kamo},
  journal={Biophysical journal},
  year={2004},
  volume={86 5},
  pages={3112-20}
}
Pharaonis phoborhodopsin (ppR, or pharaonis sensory rhodopsin II, NpsRII) is a sensor for the negative phototaxis of Natronomonas (Natronobacterium) pharaonis. Arginine 72 of ppR corresponds to Arg-82 of bacteriorhodopsin, which is a highly conserved residue among microbial rhodopsins. Using various Arg-72 ppR mutants, we obtained the following results: 1). Arg-72(ppR) together possibly with Asp-193 influenced the pK(a) of the counterion of the protonated Schiff base. 2). The M-rise became… CONTINUE READING