Role of Architecture in the Function and Specificity of Two Notch-Regulated Transcriptional Enhancer Modules

Abstract

In Drosophila melanogaster, cis-regulatory modules that are activated by the Notch cell-cell signaling pathway all contain two types of transcription factor binding sites: those for the pathway's transducing factor Suppressor of Hairless [Su(H)] and those for one or more tissue- or cell type-specific factors called "local activators." The use of different… (More)
DOI: 10.1371/journal.pgen.1002796

Topics

Cite this paper

@inproceedings{Liu2012RoleOA, title={Role of Architecture in the Function and Specificity of Two Notch-Regulated Transcriptional Enhancer Modules}, author={Feng Liu and James W Posakony}, booktitle={PLoS genetics}, year={2012} }