Role of Antipsychotic Polypharmacotherapy in the Treatment of Schizophrenia

@article{Canales1999RoleOA,
  title={Role of Antipsychotic Polypharmacotherapy in the Treatment of Schizophrenia},
  author={Patricia L. Canales and Jerry Olsen and Alexander L. Miller and M. Lynn Crismon},
  journal={CNS Drugs},
  year={1999},
  volume={12},
  pages={179-188}
}
Since the introduction of phenothiazines in the 1950s, clinicians have used anti-psychotics in combination. This practice has previously been declared irrational as traditional antipsychotics were thought to work by similar mechanisms. However, the advent of the atypical antipsychotics provides a cadre of new medications with varying pharmacodynamic profiles. Once again, the potential use of combination antipsychotic therapy is being explored.Potential advantages of combination antipsychotics… CONTINUE READING

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Antipsychotic polypharmacy or monotherapy?

  • Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology
  • 2005
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