Role of Alpha-1-Adrenergic Receptors in the Regulation of Corticotropin-Releasing Hormone mRNA in the Paraventricular Nucleus of the Hypothalamus During Stress

@article{Kiss2000RoleOA,
  title={Role of Alpha-1-Adrenergic Receptors in the Regulation of Corticotropin-Releasing Hormone mRNA in the Paraventricular Nucleus of the Hypothalamus During Stress},
  author={Alexander Kiss and Greti Aguilera},
  journal={Cellular and Molecular Neurobiology},
  year={2000},
  volume={20},
  pages={683-694}
}
AbstractSUMMARY 1. The role of α1-adrenergic receptors on CRH mRNA levels in the PVN was studied in control and stressed rats receiving i.c.v. injections of the α1-adrenergic agonist, methoxamine, or the α1- antagonist, prazosin.2. Plasma ACTH increased significantly 60 min and 4 hr after a single injection of methoxamine (100 μg, i.c.v.). No desensitization of this response was observed after repeated injections every 6 hr for 24 hr. Concomitantly, POMC mRNA in the anterior pituitary… CONTINUE READING

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References

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SHOWING 1-10 OF 39 REFERENCES

Immunohistochemical evidence for a stimulatory control by the ventral noradrenergic bundle on parvocellular corticotropin releasing hormone and vasopressin neurons in the rat

G. Alonso, A. Szafarczyk, M. Balmefrezol, I. Assenmacher
  • Brain Res
  • 1986
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Adrenergic control of the secretion of anterior pituitary hormones.

  • Bailliere's clinical endocrinology and metabolism
  • 1993
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Corticotropin-releasing factor-immunoreactive neurons of the paraventricular nucleus become vasopressin positive after adrenalectomy.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1984
VIEW 1 EXCERPT
HIGHLY INFLUENTIAL