Role of Adenosine Triphosphate and Adenosine in Oxygen-Induced Pulmonary Vasodilation in Fetal Lambs

@article{Konduri1993RoleOA,
  title={Role of Adenosine Triphosphate and Adenosine in Oxygen-Induced Pulmonary Vasodilation in Fetal Lambs},
  author={G. Ganesh Konduri and Clarisse T Gervasio and Andreas A. Theodorou},
  journal={Pediatric Research},
  year={1993},
  volume={33},
  pages={533-538}
}
ABSTRACT: We investigated the hypothesis that purine nucleotides, ATP and adenosine, mediate the pulmonary vasodilation that occurs at birth in response to an increase in arterial O2 pressure (Pao2). We studied 20 fetal lambs 1 to 3 d after placement of intravascular catheters and a flow transducer around left pulmonary artery. In 16 lambs, we investigated… CONTINUE READING