Role of Adaptive Immunity in Alcoholic Liver Disease

  title={Role of Adaptive Immunity in Alcoholic Liver Disease},
  author={Emanuele Albano},
  booktitle={International journal of hepatology},
Stimulation of innate immunity is increasingly recognized to play an important role in the pathogenesis of alcoholic liver disease (ALD), while the contribution of adaptive immunity has received less attention. Clinical and experimental data show the involvement of Th-1 and Th-17 T-lymphocytes in alcoholic hepatitis. Nonetheless, the mechanisms by which alcohol triggers adaptive immunity are still incompletely characterized. Patients with advanced ALD have circulating IgG and T-lymphocytes… CONTINUE READING