Role of ABO Secretor Status in Mucosal Innate Immunity and H. pylori Infection

  title={Role of ABO Secretor Status in Mucosal Innate Immunity and H. pylori Infection},
  author={Sara B. Linden and Jafar Mahdavi and Cristina Semino-Mora and Cara Olsen and Ingemar Carlstedt and T. Espa{\~n}ol Boren and Andr{\'e} DuBois},
  journal={PLoS Pathogens},
  pages={1892 - 1895}
The fucosylated ABH antigens, which constitute the molecular basis for the ABO blood group system, are also expressed in salivary secretions and gastrointestinal epithelia in individuals of positive secretor status; however, the biological function of the ABO blood group system is unknown. Gastric mucosa biopsies of 41 Rhesus monkeys originating from Southern Asia were analyzed by immunohistochemistry. A majority of these animals were found to be of blood group B and weak-secretor phenotype (i… CONTINUE READING
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