Role of 99mTc Sulesomab in the diagnosis of prosthetic joint infections

@article{Iyengar2005RoleO9,
  title={Role of 99mTc Sulesomab in the diagnosis of prosthetic joint infections},
  author={Karthikeyan P. Iyengar and Sobhan Vinjamuri},
  journal={Nuclear Medicine Communications},
  year={2005},
  volume={26},
  pages={489-496}
}
BackgroundInvestigation of suspected infection in prosthetic joint replacements is a difficult orthopaedic problem with important therapeutic implications. MethodsWe retrospectively analysed the results of 38 patients referred with a clinical suspicion of bone or joint infections. Referrals were made for suspected infection of prosthetic hip joints (17), total knee replacements (13), total elbow replacements (4) and total shoulder replacements (4). Sulesomab imaging was done with 650 MBq of… Expand
Use of 99mTc-Sulesomab for the Diagnosis of Prosthesis Infection after Total Joint Arthroplasty
TLDR
It was showed that 99mTc-sulesomab had good diagnostic value for the detection of prosthesis infection and the combination of 99mSulesomAB with other laboratory or imaging examinations may improve diagnostic performance in prostheses infection and should be investigated further. Expand
Radionuclide imaging: Past, present and future outlook in the diagnosis of infected prosthetic joints.
TLDR
A serious complication of joint replacement surgery is infection, which results in prolonged invalidity as well as removal and subsequent re-implantation after lengthy antibiotic therapy, and radionuclide imaging has come to aid in the diagnostic imaging in the failed joint replacement. Expand
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TLDR
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Value of antigranulocyte scintigraphy with Tc-99m-sulesomab in diagnosing combat-related infections of the musculoskeletal system
TLDR
Three-phase bone scanning did not deliver any diagnostic benefit, since no result was able to differentiate unequivocally between infection-related and reactive changes, and antigranulocyte scintigraphy using Tc-99m-sulesomab represented a highly suitable technique for diagnostically clarifying combat-related infections of the extremities. Expand
Prosthesis infection: diagnosis after total joint arthroplasty with antigranulocyte scintigraphy with 99mTc-labeled monoclonal antibodies--a meta-analysis.
TLDR
AGS with monoclonal antibodies had a reasonably high discriminating ability to identify prosthesis infection in patients who underwent total joint arthroplasty. Expand
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TLDR
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Diagnosis of Periprosthetic Joint Infection: The Role of Nuclear Medicine May Be Overestimated.
TLDR
The use of nuclear imaging for diagnosis of PJI should be limited to a few select cases, due to high risk of bias as well as high levels of concern regarding the clinical applicability of these tests. Expand
Nuclear medicine imaging of bone infections.
TLDR
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Use of Anti-Granulocyte Scintigraphy with 99mTc-Labeled Monoclonal Antibodies for the Diagnosis of Periprosthetic Infection in Patients after Total Joint Arthroplasty: A Diagnostic Meta-Analysis
TLDR
Anti-granulocyte scintigraphy using 99 mTc-labeled monoclonal antibodies has a reasonable role in the diagnosis of PJI after total joint arthroplasty and additional high-quality original studies are required to confirm the predictive value. Expand
A preformed antibiotic-loaded spacer for treatment for septic arthritis of the shoulder
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