Role of 5-HT5A receptors in the consolidation of memory

@article{Gonzalez2013RoleO5,
  title={Role of 5-HT5A receptors in the consolidation of memory},
  author={R. Gonzalez and Karla Ch{\'a}vez-Pascacio and A. Meneses},
  journal={Behavioural Brain Research},
  year={2013},
  volume={252},
  pages={246-251}
}
  • R. Gonzalez, Karla Chávez-Pascacio, A. Meneses
  • Published 2013
  • Psychology, Medicine
  • Behavioural Brain Research
  • 5-HT5 receptor occurs in brain areas implicated in learning and memory. Hence, the effects (0.01-3.0 mg/kg) of SB-6995516 (a 5-HT5A receptor antagonist) in the associative learning task of autoshaping were studied. The results showed that post-training injection of SB-699551 decreased conditioned responses (CR) during short-term (STM; 1.5h; at 0.1mg/kg) and long-term memory (LTM; 24 h; at 3.0 mg/kg) relative to the vehicle animals. Moreover, considering that there are no selective 5-HT5A… CONTINUE READING
    36 Citations

    Topics from this paper

    The Role of Hippocampal 5HT3 Receptors in Harmaline-Induced Memory Deficit
    • M. Nasehi
    • Psychology, Medicine
    • Basic and clinical neuroscience
    • 2015
    • 3
    • PDF
    Memory formation and memory alterations: 5-HT6 and 5-HT7 receptors, novel alternative
    • A. Meneses
    • Psychology, Medicine
    • Reviews in the neurosciences
    • 2014
    • 38
    Serotonergic 5-HT7 receptors and cognition
    • 34

    References

    SHOWING 1-10 OF 29 REFERENCES
    Do serotonin1–7 receptors modulate short and long-term memory?
    • A. Meneses
    • Chemistry
    • Neurobiology of Learning and Memory
    • 2007
    • 60
    Effect of 5-HT5A antagonists in animal models of schizophrenia, anxiety and depression
    • 19
    5-ht5A receptors as a therapeutic target.
    • D. R. Thomas
    • Biology, Medicine
    • Pharmacology & therapeutics
    • 2006
    • 67