Role of 4-hydroxy-trans-2-nonenal in cell functions

Abstract

The role of lipid peroxidation product 4-hydroxy-trans-2-nonenal (4-HNE) in functional activity of cells under normal and different pathological conditions is discussed. Different pathways of 4-HNE metabolism in tissues are analyzed, with particular focus on the role the glutathione system in this process. 4-HNE is implicated in regulation of cell growth… (More)
DOI: 10.1134/S0006297910090014

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