Role of 18F‐FDOPA PET/CT imaging in endocrinology

  title={Role of 18F‐FDOPA PET/CT imaging in endocrinology},
  author={P. Santhanam and D. Ta{\"i}eb},
  journal={Clinical Endocrinology},
  • P. Santhanam, D. Taïeb
  • Published 2014
  • Medicine
  • Clinical Endocrinology
  • 18F‐FDOPA (6‐[18F]‐L‐fluoro‐L‐3, 4‐dihydroxyphenylalanine)‐based PET/CT imaging can be a useful tool for the detection of different neuroendocrine tumours (NETs). 18F‐FDOPA is taken up into the cells via the neutral amino acid transporter (LAT1/4F2hc). This transporter is also coupled to the mammalian target of rapamycin (mTOR) signalling pathway. 18F‐FDOPA PET/CT may be performed for confirmation of diagnosis of pheochromocytoma/paraganglioma, staging at initial presentation, restaging and… CONTINUE READING
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