Role of α1 adrenergic antagonism in the mechanism of action of iloperidone: reducing extrapyramidal symptoms.

@article{Stahl2013RoleO,
  title={Role of α1 adrenergic antagonism in the mechanism of action of iloperidone: reducing extrapyramidal symptoms.},
  author={Stephen M. Stahl},
  journal={CNS spectrums},
  year={2013},
  volume={18 6},
  pages={285-8}
}
ISSUE The low incidence of extrapyramidal side effects associated with the atypical antipsychotic iloperidone may be linked to its unique binding profile of high affinity antagonism of both α1 adrenergic receptors and serotonin 2A receptors. 
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Stahl’s Essential Psychopharmacology, 4th ed

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