Role of α-relaxation on crystallization of amorphous celecoxib above T(g) probed by dielectric spectroscopy.

@article{Dantuluri2011RoleO,
  title={Role of α-relaxation on crystallization of amorphous celecoxib above T(g) probed by dielectric spectroscopy.},
  author={Ajay Kumar Raju Dantuluri and Aeshna Amin and Vibha Puri and Arvind K Bansal},
  journal={Molecular pharmaceutics},
  year={2011},
  volume={8 3},
  pages={814-22}
}
In the present study, the role of α-relaxation toward isothermal crystallization of amorphous celecoxib was studied using dielectric spectroscopy (DES). The dielectric response of the α-relaxation was measured as a function of frequency (10⁻¹ to 10⁶ Hz), isothermally at every 4 K interval in the range of 303.15 to 443.15 K. The dielectric loss spectrum at each temperature was analyzed using the Havriliak Negami (HN) equation to extract the characteristic relaxation time, τ(HN). Two Vogel… CONTINUE READING
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