Role in depression of a multi-fractionated versus a conventional Hypericum perforatum extract.

@article{Pierro2018RoleID,
  title={Role in depression of a multi-fractionated versus a conventional Hypericum perforatum extract.},
  author={Francesco Di Pierro and Paolo Risso and Roberto Settembre},
  journal={Panminerva medica},
  year={2018},
  volume={60 4},
  pages={
          156-160
        }
}
BACKGROUND Hypericum perforatum is used as medicinal plant for mild to moderately severe depression. Several trials have found hypericum to be more effective than placebo or some antidepressant drugs, but the exact mechanism and most relevant compounds are still unclear. A possible hypothesis is that the antidepressant activity might be due to its multiplicity of bioactive compounds. Aim is to test if greater chemical complexity could result in a greater hypericum antidepressant action… CONTINUE READING
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