Role in T-cell activation for HLA class I molecules from accessory cells: further distinction between activation signals delivered to T cells via CD2 and CD3 molecules.

@article{Huet1987RoleIT,
  title={Role in T-cell activation for HLA class I molecules from accessory cells: further distinction between activation signals delivered to T cells via CD2 and CD3 molecules.},
  author={Sylvie Huet and Laurence Boumsell and Brigitte Raynal and Laurent Degos and J. C. Dausset and Albert G. Bernard},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1987},
  volume={84 20},
  pages={
          7222-6
        }
}
The immunological function of major histocompatibility complex molecules, including HLA class I molecules, is to present antigens and/or their processed peptides to various lymphocyte subpopulations. Thus, they play a pivotal role in regulatory interactions between cells of the immune system, which can result in the activation and function of T cells. We looked for a role of major histocompatibility complex molecules during T-cell activation induced by monoclonal antibody (mAb) or combinations… CONTINUE READING
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