Role for the Ankyrin eukaryotic-like genes of Legionella pneumophila in parasitism of protozoan hosts and human macrophages.

@article{Habyarimana2008RoleFT,
  title={Role for the Ankyrin eukaryotic-like genes of Legionella pneumophila in parasitism of protozoan hosts and human macrophages.},
  author={Fabien Habyarimana and Souhaila Al-Khodor and Awdhesh Kalia and James E. Graham and Christopher T. D. Price and M. Teresa Garc{\'i}a and Yousef Abu Kwaik},
  journal={Environmental microbiology},
  year={2008},
  volume={10 6},
  pages={1460-74}
}
Legionella pneumophila is a ubiquitous organism in the aquatic environment where it is capable of invasion and intracellular proliferation within various protozoan species and is also capable of causing pneumonia in humans. In silico analysis showed that the three sequenced L. pneumophila genomes each contained a common multigene family of 11 ankyrin (ank) genes encoding proteins with approximately 30-35 amino acid tandem Ankyrin repeats that are involved in protein-protein interactions in… CONTINUE READING

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