Role for sterol regulatory element-binding protein in activation of endothelial cells by phospholipid oxidation products.

Abstract

Oxidized phospholipids, including oxidation products of palmitoyl-arachidonyl-phosphatidyl choline (PAPC), are mediators of inflammation in endothelial cells (ECs) and known to induce several chemokines, including interleukin-8 (IL-8). In this study, we show that oxidized PAPC (OxPAPC), which accumulates in atherosclerotic lesions, paradoxically depletes… (More)

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Cite this paper

@article{Yeh2004RoleFS, title={Role for sterol regulatory element-binding protein in activation of endothelial cells by phospholipid oxidation products.}, author={Michael Yeh and Alexander M. Cole and Jenny J Choi and Yi Liu and Dmitry Tulchinsky and Jian-hua Qiao and Michael C. Fishbein and Alek N. Dooley and Talin Hovnanian and Kevin Mouilleseaux and Devendra K. Vora and Wen-pin Yang and Peter S. Gargalovic and Todd G. Kirchgessner and John Shyy and Judith A. Berliner}, journal={Circulation research}, year={2004}, volume={95 8}, pages={780-8} }