Role for heat shock proteins in the immune response to measles virus infection.

@article{Oglesbee2002RoleFH,
  title={Role for heat shock proteins in the immune response to measles virus infection.},
  author={Michael J Oglesbee and Mary Pratt and Thomas Carsillo},
  journal={Viral immunology},
  year={2002},
  volume={15 3},
  pages={399-416}
}
Heat shock proteins (HSPs) are recognized for their support of protein metabolism. Interaction with viral proteins also enhances the development of innate and adaptive immune responses against the infecting agent. At the level of the infected cell, HSPs are uniquely expressed on the cell surface, where they represent targets of lymphokine activated killer cells. Necrosis of the infected cell releases complexes of HSP and viral protein, which, in turn, binds antigen-presenting cells (APCs). One… CONTINUE READING

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