Role for angiotensin II in an overt functional proteinuria.

  title={Role for angiotensin II in an overt functional proteinuria.},
  author={Tadao Yoshioka and Tetsuya Mitarai and Valentina Kon and William M. Deen and Helmut G. Rennke and Iekuni Ichikawa},
  journal={Kidney international},
  volume={30 4},
A partial renal vein constriction (RVC) was induced acutely in Munich-Wistar rats. RVC caused a marked reduction in glomerular plasma flow rate, and rises in glomerular transcapillary hydraulic pressure difference and efferent arteriolar resistance. These changes were associated with a marked increase in urinary protein excretion, on average from a baseline level of 8 to approximately 120 mg/24 hrs per kidney. Infusion of saralasin, an angiotensin II (AII) antagonist, largely normalized these… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 46 extracted citations

Similar Papers

Loading similar papers…