Corpus ID: 14089149

Role and distribution of serotonin type 2A receptors in Alzheimer’s disease

@inproceedings{2003RoleAD,
  title={Role and distribution of serotonin type 2A receptors in Alzheimer’s disease},
  author={},
  year={2003}
}
  • Published 2003
Serotonin (5-HT) and more specifically the 5-HT2A receptor is involved in cognitive and non-cognitive behavior and plays an important role in Alzheimer’s disease (AD). The objective was to assess the 5HT2A binding potential (BP) in healthy volunteers and AD with SPECT and I-5-I-R91150, a selective radio-iodinated 5-HT2A receptor antagonist. Twenty-six controls and 9 AD patients were included. A semiquantitive analysis with normalization on cerebellar uptake provided estimates of BP for 26… Expand

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