Role and contribution of pulmonary CD103+ dendritic cells in the adaptive immune response to Mycobacterium tuberculosis.

@article{Koh2017RoleAC,
  title={Role and contribution of pulmonary CD103+ dendritic cells in the adaptive immune response to Mycobacterium tuberculosis.},
  author={Vanessa Hui Qi Koh and See Liang Ng and Michelle Lay Teng Ang and Wenwei Lin and Christiane Ruedl and S. Miguel Alonso},
  journal={Tuberculosis},
  year={2017},
  volume={102},
  pages={34-46}
}
Despite international control programmes, the global burden of tuberculosis remains enormous. Efforts to discover novel drugs have largely focused on targeting the bacterium directly. Alternatively, manipulating the host immune response may represent a valuable approach to enhance immunological clearance of the bacilli, but necessitates a deeper understanding of the immune mechanisms associated with protection against Mycobacterium tuberculosis infection. Here, we examined the various dendritic… CONTINUE READING

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