Role and Regulation of Myeloid Zinc Finger Protein 1 in Cancer.

@article{Eguchi2015RoleAR,
  title={Role and Regulation of Myeloid Zinc Finger Protein 1 in Cancer.},
  author={Taka Eguchi and Thomas L. Prince and Barbara Wegiel and Stuart K. Calderwood},
  journal={Journal of cellular biochemistry},
  year={2015},
  volume={116 10},
  pages={
          2146-54
        }
}
Myeloid zinc finger 1 (MZF1) belongs to the SCAN-Zinc Finger (SCAN-ZF) transcription factor family that has recently been implicated in a number of types of cancer. Although the initial studies concentrated on the role of MZF1 in myeloid differentiation and leukemia, the factor now appears to be involved in the etiology of major solid tumors such as lung, cervical, breast, and colorectal cancer. Here we discuss the regulation of MZF1 that mediated its recruitment and activation in cancer… CONTINUE READING

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