Roflumilast: doubtful efficacy but clear harms in COPD.

  title={Roflumilast: doubtful efficacy but clear harms in COPD.},
  journal={Prescrire international},
  volume={22 134},
  • Published 2013 in Prescrire international
Avoidance of irritants such as tobacco smoke slows the progression of severe chronic obstructive pulmonary disease (COPD). Drugs have only a modest, purely symptomatic effect; a bronchodilator is combined with an inhaled corticosteroid when exacerbations are frequent. Oxygen therapy prolongs survival in very severe disease. Roflumilast, a nonsteroidal… CONTINUE READING