Rodent stroke induced by photochemical occlusion of proximal middle cerebral artery: evolution monitored with MR imaging and histopathology.

@article{Chen2007RodentSI,
  title={Rodent stroke induced by photochemical occlusion of proximal middle cerebral artery: evolution monitored with MR imaging and histopathology.},
  author={Feng Chen and Yasuhiro Suzuki and Nobuo Nagai and Lixin Jin and Jie Yu and Huaijun Wang and Guy Marchal and Yicheng Ni},
  journal={European journal of radiology},
  year={2007},
  volume={63 1},
  pages={68-75}
}
PURPOSE To longitudinally investigate stroke in rats after photothrombotic occlusion of proximal middle cerebral artery (MCA) with magnetic resonance imaging (MRI) in correlation with histopathology. MATERIALS AND METHODS Forty-two rats were subjected to photochemical MCA occlusion and MRI at 1.5T, and sacrificed in seven groups (n=6 each) at the following time points: 1, 3, 6 and 12h, and at day 1, 3 and 9. T2-weighted (T2WI) and diffusion-weighted imaging (DWI) with apparent diffusion… CONTINUE READING
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