Rodent animal models of delayed bone healing and non-union formation: a comprehensive review.

@article{Garcia2013RodentAM,
  title={Rodent animal models of delayed bone healing and non-union formation: a comprehensive review.},
  author={Patric Garcia and T. Scheuer Histing and J{\"o}rg Holstein and Moritz Klein and Matthias W Laschke and Romano Matthys and Anita Ignatius and Britt Wildemann and Jasmin Lienau and Anja Peters and Bettina M Willie and georg. duda and Lutz Claes and Tim Pohlemann and Michael Dieter Menger},
  journal={European cells & materials},
  year={2013},
  volume={26},
  pages={
          1-12; discussion 12-4
        }
}
Despite the growing knowledge on the mechanisms of fracture healing, delayed healing and non-union formation remain a major clinical challenge. Animal models are needed to study the complex process of normal and impaired fracture healing and to develop new therapeutic strategies. Whereas in the past mainly large animals have been used to study normal and impaired fracture healing, nowadays rodent models are of increasing interest. New osteosynthesis techniques for rat and mice have been… CONTINUE READING
Highly Cited
This paper has 50 citations. REVIEW CITATIONS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 26 extracted citations

A new animal model for delayed osseous union secondary to osteitis.

BMC musculoskeletal disorders • 2015
View 4 Excerpts
Highly Influenced

fewer than 50 Citations

01020'14'15'16'17'18'19
Citations per Year
Semantic Scholar estimates that this publication has 50 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 27 references

Influence of flexible nailing in the later phase of fracture healing: strength and mineralization in rat femora.

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association • 2001
View 3 Excerpts
Highly Influenced

The effects of cisplatin on the incorporation of fresh syngeneic and frozen allogeneic cortical bone grafts

Journal of orthopaedic research : official publication of the Orthopaedic Research Society • 1993
View 1 Excerpt
Highly Influenced

The effect of diabetes mellitus on osseous healing.

Clinical oral implants research • 2010
View 1 Excerpt