Robustness of signal transduction pathways

@article{Blthgen2012RobustnessOS,
  title={Robustness of signal transduction pathways},
  author={Nils Bl{\"u}thgen and Stefan Legewie},
  journal={Cellular and Molecular Life Sciences},
  year={2012},
  volume={70},
  pages={2259-2269}
}
Signal transduction pathways transduce information about the outside of the cell to the nucleus, regulating gene expression and cell fate. To reliably inform the cell about its surroundings, information transfer has to be robust against typical perturbation that a cell experiences. Robustness of several mammalian signaling pathways has been studied recently… CONTINUE READING