Robustness of positional specification by the Hedgehog morphogen gradient.

Abstract

Spatial gradients of Hedgehog signalling play a central role in many patterning events during animal development, regulating cell fate determination and tissue growth in a variety of tissues and developmental stages. Experimental evidence suggests that many of the proteins responsible for regulating Hedgehog signalling and transport are themselves targets… (More)
DOI: 10.1016/j.ydbio.2010.03.022

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