Robustness of RNA sequencing on older formalin-fixed paraffin-embedded tissue from high-grade ovarian serous adenocarcinomas

@inproceedings{Zhao2019RobustnessOR,
  title={Robustness of RNA sequencing on older formalin-fixed paraffin-embedded tissue from high-grade ovarian serous adenocarcinomas},
  author={Yongmei Zhao and Monika Mehta and Ashley Walton and Keyur Talsania and Yelena Levin and Jyoti Shetty and Elizabeth Gillanders and Bao Qui Tran and Danielle Mercatante Carrick},
  booktitle={PloS one},
  year={2019}
}
Formalin-fixed paraffin-embedded (FFPE) tissues are among the most widely available clinical specimens. Their potential utility as a source of RNA for transcriptome studies would greatly enhance population-based cancer studies. Although preliminary studies suggest FFPE tissue may be used for RNA sequencing, the effect of storage time on these specimens needs to be determined. We conducted this study to determine whether RNA in archived FFPE high-grade ovarian serous adenocarcinomas from… CONTINUE READING
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