Robustness analysis and tuning of synthetic gene networks

@article{Batt2007RobustnessAA,
  title={Robustness analysis and tuning of synthetic gene networks},
  author={Gr{\'e}gory Batt and Boyan Yordanov and Ron Weiss and Calin Belta},
  journal={Bioinformatics},
  year={2007},
  volume={23 18},
  pages={2415-22}
}
MOTIVATION The goal of synthetic biology is to design and construct biological systems that present a desired behavior. The construction of synthetic gene networks implementing simple functions has demonstrated the feasibility of this approach. However, the design of these networks is difficult, notably because existing techniques and tools are not adapted to deal with uncertainties on molecular concentrations and parameter values. RESULTS We propose an approach for the analysis of a class of… CONTINUE READING
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