Robust vaccine-elicited cellular immune responses in breast milk following systemic simian immunodeficiency virus DNA prime and live virus vector boost vaccination of lactating rhesus monkeys.

@article{Wilks2010RobustVC,
  title={Robust vaccine-elicited cellular immune responses in breast milk following systemic simian immunodeficiency virus DNA prime and live virus vector boost vaccination of lactating rhesus monkeys.},
  author={Andrew B. Wilks and Elizabeth C. Christian and Michael S. Seaman and Piya Sircar and Angela Carville and Carmen Elena G{\'o}mez and M Carmen Desco Esteban and Giuseppe Pantaleo and Dan H Barouch and Norman L. Letvin and Sallie R. Permar},
  journal={Journal of immunology},
  year={2010},
  volume={185 11},
  pages={7097-106}
}
Breast milk transmission of HIV remains an important mode of infant HIV acquisition. Enhancement of mucosal HIV-specific immune responses in milk of HIV-infected mothers through vaccination may reduce milk virus load or protect against virus transmission in the infant gastrointestinal tract. However, the ability of HIV/SIV strategies to induce virus-specific immune responses in milk has not been studied. In this study, five uninfected, hormone-induced lactating, Mamu A*01(+) female rhesus… CONTINUE READING

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MOPH-TAVEG The Journal of Immunology 7105 at N rth D aota State U iv L ib/Piodicals D pt on M ay 22, 2015 hp://w w w jim m unl.org/ D ow nladed from Investigators

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