Robust regression-based analysis of drug-nucleic acid binding.

Abstract

Outlier detection can be very important in analyzing data from Scatchard plots. In this study, a robust (outlier-resistant) regression procedure was used in conjunction with a Scatchard plot to study the binding of the methylphenazinium cation with double-stranded DNA. The procedures, their results, and their advantages are discussed.

Cite this paper

@article{Booth2003RobustRA, title={Robust regression-based analysis of drug-nucleic acid binding.}, author={David Booth and Kidong Lee}, journal={Analytical biochemistry}, year={2003}, volume={319 2}, pages={258-62} }