Robust ranks of true associations in genome-wide case-control association studies

@article{Zheng2007RobustRO,
  title={Robust ranks of true associations in genome-wide case-control association studies},
  author={G Zheng and Jungnam Joo and J X Lin and Mario P. Stylianou and Myron A. Waclawiw and Nancy L. Geller},
  journal={BMC Proceedings},
  year={2007},
  volume={1},
  pages={S165 - S165}
}
In whole-genome association studies, at the first stage, all markers are tested for association and their test statistics or p-values are ranked. At the second stage, some most significant markers are further analyzed by more powerful statistical methods. This helps reduce the number of hypotheses to be corrected for in multiple testing. Ranks of true… CONTINUE READING