Robust model-based analysis of single-particle tracking experiments with Spot-On

Abstract

Single-particle tracking (SPT) has become an important method to bridge biochemistry and cell biology since it allows direct observation of protein binding and diffusion dynamics in live cells. However, accurately inferring information from SPT studies is challenging due to biases in both data analysis and experimental design. To address analysis bias, we… (More)
DOI: 10.7554/eLife.33125

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