Robust meta-analysis of gene expression using the elastic net

@inproceedings{Hughey2015RobustMO,
  title={Robust meta-analysis of gene expression using the elastic net},
  author={Jacob J. Hughey and Atul J Butte},
  booktitle={Nucleic acids research},
  year={2015}
}
Meta-analysis of gene expression has enabled numerous insights into biological systems, but current methods have several limitations. We developed a method to perform a meta-analysis using the elastic net, a powerful and versatile approach for classification and regression. To demonstrate the utility of our method, we conducted a meta-analysis of lung cancer gene expression based on publicly available data. Using 629 samples from five data sets, we trained a multinomial classifier to… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 19 times. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 42 references

Diagnosis of multiple cancer types by shrunken centroids of gene expression.

Proceedings of the National Academy of Sciences of the United States of America • 2002
View 6 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…