Robust and accurate quantification of biomarkers of immune cells in lung cancer micro-environment using deep convolutional neural networks

@inproceedings{Aprupe2019RobustAA,
  title={Robust and accurate quantification of biomarkers of immune cells in lung cancer micro-environment using deep convolutional neural networks},
  author={Lilija Aprupe and Geert J. S. Litjens and Titus Josef Brinker and Jeroen van der Laak and Niels Grabe},
  booktitle={PeerJ},
  year={2019}
}
Recent years have seen a growing awareness of the role the immune system plays in successful cancer treatment, especially in novel therapies like immunotherapy. The characterization of the immunological composition of tumors and their micro-environment is thus becoming a necessity. In this paper we introduce a deep learning-based immune cell detection and quantification method, which is based on supervised learning, i.e., the input data for training comprises labeled images. Our approach… CONTINUE READING
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