Robust Identification of Large Genetic Networks

  title={Robust Identification of Large Genetic Networks},
  author={Diego di Bernardo and Timothy S. Gardner and James J. Collins},
  journal={Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing},
Temporal and spatial gene expression, together with the concentration of proteins and metabolites, is tightly controlled in the cell. This is possible thanks to complex regulatory networks between these different elements. The identification of these networks would be extremely valuable. We developed a novel algorithm to identify a large genetic network, as a set of linear differential equations, starting from measurements of gene expression at steady state following transcriptional… CONTINUE READING