Robust Identification of Alzheimer’s Disease subtypes based on cortical atrophy patterns


Accumulating evidence suggests that Alzheimer's disease (AD) is heterogenous and can be classified into several subtypes. Here, we propose a robust subtyping method for AD based on cortical atrophy patterns and graph theory. We calculated similarities between subjects in their atrophy patterns throughout the whole brain, and clustered subjects with similar… (More)
DOI: 10.1038/srep43270