Robo3-Driven Axon Midline Crossing Conditions Functional Maturation of a Large Commissural Synapse

@article{Michalski2013Robo3DrivenAM,
  title={Robo3-Driven Axon Midline Crossing Conditions Functional Maturation of a Large Commissural Synapse},
  author={Nicolas Michalski and Norbert Babai and Nicolas Renier and David J Perkel and Alain Ch{\'e}dotal and Ralf Schneggenburger},
  journal={Neuron},
  year={2013},
  volume={78},
  pages={855-868}
}
During the formation of neuronal circuits, axon pathfinding decisions specify the location of synapses on the correct brain side and in correct target areas. We investigated a possible link between axon midline crossing and the subsequent development of output synapses formed by these axons. Conditional knockout of Robo3 in the auditory system forced a large commissural synapse, the calyx of Held, to be exclusively formed on the wrong, ipsilateral side. Ipsilateral calyx of Held synapses showed… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS
6 Extracted Citations
64 Extracted References
Similar Papers

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 64 references

Similar Papers

Loading similar papers…