Robert Boyle's landmark book of 1660 with the first experiments on rarified air.

@article{West2005RobertBL,
  title={Robert Boyle's landmark book of 1660 with the first experiments on rarified air.},
  author={John B West},
  journal={Journal of applied physiology},
  year={2005},
  volume={98 1},
  pages={
          31-9
        }
}
  • J. West
  • Published 2005
  • Physics
  • Journal of applied physiology
In 1660, Robert Boyle (1627-1691) published his landmark book New Experiments Physico-Mechanicall, Touching the Spring of the Air, and its Effects... in which he described the first controlled experiments of the effects of reducing the pressure of the air. Critical to this work was the development of an air pump by Boyle with Robert Hooke (1635-1703). For the first time, it was possible to observe physical and physiological processes at both normal and reduced barometric pressures. The air pump… 

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TLDR
When Boyle's data are plotted by using modern conventional methods, they strongly support his hypothesis that the volume and pressure of a gas are inversely related.
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