Rituximab is effective in the treatment of refractory ophthalmic Wegener's granulomatosis.

@article{Taylor2009RituximabIE,
  title={Rituximab is effective in the treatment of refractory ophthalmic Wegener's granulomatosis.},
  author={Simon R.J. Taylor and Alan David Salama and Lavnish Joshi and Charles Dickson Pusey and Susan L. Lightman},
  journal={Arthritis and rheumatism},
  year={2009},
  volume={60 5},
  pages={1540-7}
}
OBJECTIVE To investigate the efficacy of rituximab in patients with refractory ophthalmic Wegener's granulomatosis (WG). METHODS Data from 10 consecutive patients with refractory ophthalmic WG treated with rituximab were retrospectively reviewed. In all patients, the ophthalmic disease was driving treatment decisions, and disease activity had persisted despite standard immunosuppressive treatment. Patients had refractory scleritis (n=3), orbital granulomas causing optic nerve compromise (n=4… CONTINUE READING
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