Rituximab for the treatment of juvenile dermatomyositis: a report of four pediatric patients.

@article{Cooper2007RituximabFT,
  title={Rituximab for the treatment of juvenile dermatomyositis: a report of four pediatric patients.},
  author={Megan A Cooper and Donna L Willingham and Diane E. Brown and Anthony R. French and Fei F. Shih and A J White},
  journal={Arthritis and rheumatism},
  year={2007},
  volume={56 9},
  pages={3107-11}
}
OBJECTIVE Juvenile dermatomyositis (DM) is a chronic inflammatory myopathy of childhood primarily affecting the muscles and skin. Treatment for juvenile DM is often difficult, and conventional therapies include corticosteroids and other immune suppressants. We reviewed the records of 4 patients with juvenile DM who received the B cell-depleting anti-CD20 monoclonal antibody rituximab to determine whether this therapy resulted in improved control of their juvenile DM. METHODS This is a… CONTINUE READING

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