Rituximab-associated infections.
@article{GeaBanacloche2010RituximabassociatedI, title={Rituximab-associated infections.}, author={Juan C. Gea-Banacloche}, journal={Seminars in hematology}, year={2010}, volume={47 2}, pages={ 187-98 } }
After more than 10 years of use, rituximab has proven to be remarkably safe. However, accumulated evidence now suggests that under some circumstances it may significantly increase the risk of infections. This risk is difficult to quantify because of confounding factors (namely, concomitant use of immunosuppressive or chemotherapeutic agents and underlying conditions), as well as under-reporting. Increased number of infections has been documented in patients treated with maintenance rituximab…
229 Citations
Management of patients with overt or resolved hepatitis B virus infection undergoing rituximab therapy
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- 2014
The safety of RTX in patients with overt or resolved HBV infection, providing recommendations for its safe use in such patients is reviewed.
Rituximab-Associated Occurrence of Disseminated Miliary Tuberculosis
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- Medicine, BiologyInternational journal of STD & AIDS
- 2020
The outcome of four PLWH who underwent RTX therapy after the diagnosis of immune-mediated renal disease was described, and the main RTX-associated adverse effects were leukopenia, late-onset neutropenia and decline of CD4+ and CD8+ T-cell counts.
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- Medicine, BiologyBMC medicine
- 2011
R-C is superior to standard C in terms of overall response and it does not increase the overall incidence of severe infection, and more studies are needed to explore the potential effect of R on silent and chronic viral infections.
Prolonged Immunodeficiency in a Patient with Burkitt's Lymphoma after Treatment with Rituximab and Chemotherapy
- Medicine, Biology
- 2014
The need for an immunological work-up in lymphoma patients before initiation of treatment is illustrated because of the increased incidence of lymphoma in patients with immunodeficiencies.
INFECTIOUS COMPLICATIONS AS A PREDICTOR OF MORTALITY IN PATIENTS WITH NON-HODGKIN LYMPHOMA RECEIVING RITUXIMAB-CONTAINING CHEMOTHERAPY.
- MedicineRevista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion
- 2019
Multivariate analysis for mortality showed that age >60 years, failure to achieve a complete response, and development of an infectious complication increased the risk of death, and it is important to perform a screening test for TB in patients who will receive rituximab and maintain a constant monitoring to detect an infectious process and begin treatment as soon as possible.
A case of severe acute hepatitis C and delayed antibody production due to rituximab therapy
- Medicine, BiologyClinical journal of gastroenterology
- 2010
The long window (8 months) between HCV infection and the development of anti-HCV antibodies observed in the present case may have been due to a B cell disorder caused by rituximab therapy.
Development of Enteroviral Aseptic Meningitis After Rituximab Treatment of Non-Hodgkin Lymphoma
- Medicine, Biology
- 2012
A case of aseptic meningitis is reported in a patient with non-Hodgkin lymphoma after treatment with rituximab in combination with cytotoxic chemotherapy and successful treatment with intravenous immunoglobulin therapy.
Severe hepatitis associated with varicella zoster virus infection in a patient with diffuse large B cell lymphoma treated with rituximab-CHOP chemotherapy
- Medicine, BiologyInternational Journal of Hematology
- 2012
It is suggested that the use of chemotherapy for immune-suppressed elderly lymphoma patients may involve the risk of severe VZV infection, particularly in patients who are not recipients of hematopoietic stem cell transplantation.
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