Rituximab Downregulates Gene Expression Associated with Cell Proliferation, Survival, and Proteolysis in the Peripheral Blood from Rheumatoid Arthritis Patients: A Link between High Baseline Autophagy-Related ULK1 Expression and Improved Pain Control

Abstract

Objective. To clarify molecular mechanisms for the response to rituximab in a longitudinal study. Methods. Peripheral blood from 16 RA patients treated with rituximab for a single treatment course and 26 healthy controls, blood and knee articular cartilages from 18 patients with long-standing RA, and cartilages from 14 healthy subjects were examined… (More)
DOI: 10.1155/2016/4963950

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@inproceedings{Tchetina2016RituximabDG, title={Rituximab Downregulates Gene Expression Associated with Cell Proliferation, Survival, and Proteolysis in the Peripheral Blood from Rheumatoid Arthritis Patients: A Link between High Baseline Autophagy-Related ULK1 Expression and Improved Pain Control}, author={Elena V Tchetina and Anastasya N. Pivanova and Galina A. Markova and Galina V Lukina and Elena N Aleksandrova and Andrey P. Aleksankin and Sergey A. Makarov and Aleksandr N. Kuzin}, booktitle={Arthritis}, year={2016} }