Risperidone in children with autism and serious behavioral problems.

  title={Risperidone in children with autism and serious behavioral problems.},
  author={James Thomas Mccracken and James J. McGough and Bhupendra Shah and Patricia L. E. Cronin and Daniel C. Hong and Michael G. Aman and Lillian E. Arnold and R. Matthews Lindsay and Patricia L. Nash and Jill A. Hollway and Christopher J. Mcdougle and David J. Posey and Naomi B. Swiezy and Arlene E. Kohn and Lawrence Scahill and Andr{\'e}s Barriga Mart{\'i}n and Kathleen K{\"o}nig and Fred Volkmar and Deirdre H. Carroll and Allison Lancor and Elaine Tierney and Jaswinder Kaur Ghuman and Norberto M. Gonzalez and Marco A Grados and Benedetto Vitiello and Louise Ritz and Mark Davies and James Beresford Robinson and Don D McMahon},
  journal={The New England journal of medicine},
  volume={347 5},
BACKGROUND Atypical antipsychotic agents, which block postsynaptic dopamine and serotonin receptors, have advantages over traditional antipsychotic medications in the treatment of adults with schizophrenia and may be beneficial in children with autistic disorder who have serious behavioral disturbances. However, data on the safety and efficacy of atypical antipsychotic agents in children are limited. METHODS We conducted a multisite, randomized, double-blind trial of risperidone as compared… CONTINUE READING


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